The Ultimate 3-Week Itinerary in Peru and Bolivia

Planning a 3-week itinerary through Peru and Bolivia?

Great choice!

This route is packed with breathtaking landscapes, ancient history, and authentic local culture.

To help you organize your trip, I’ve put together a complete 21-day Peru-Bolivia itinerary that covers the most iconic highlights and practical travel tips along the way.

You’ll start in Lima, Peru’s vibrant capital, then make your way through the colonial charm of Arequipa and the majestic Colca Canyon, before heading to Cusco, the Sacred Valley, and the unforgettable Machu Picchu. From there, cross into Bolivia to discover the magic of Lake Titicaca, explore colorful La Paz, and end with the surreal beauty of the Salar de Uyuni and Sur Lípez.

Throughout this guide, I’ll share my top tips, route suggestions, and accommodation recommendations for every budget to help you make the most of your adventure—without feeling rushed.

So, how do you travel through Peru and Bolivia in 3 weeks?

Let’s dive in!

Peru and Bolivia Itinerary

1) Lima (2 days)

Lima, the capital of Peru, is the perfect starting point for any journey through Peru and Bolivia.

With a population of 10 million, this bustling city has plenty to offer across its diverse neighborhoods.

Day 1 – Exploring Lima
Start your adventure in two of the city’s most vibrant districts: Miraflores and Barranco.

Begin your day in Miraflores with a visit to Huaca Pucllana, a fascinating pre-Inca and Inca archaeological site that dates back over 1,500 years.

Then, take a walk along the Malecón, a scenic clifftop promenade overlooking the Pacific Ocean. You’ll enjoy breathtaking views of the coastline, surfers riding the waves, and lush green parks along the way.

Make a stop at the Parque del Amor, home to the famous sculpture “El Beso” by renowned Peruvian artist Víctor Delfín.

Continue to Larcomar, a shopping and entertainment center placed above the ocean, featuring boutiques, cafés, and restaurants with stunning terrace views.

From there, head down Avenida José Larco to Parque Kennedy, the heart of Miraflores. Nearby, explore the Surquillo Market, where you’ll find an incredible variety of local ingredients, from exotic fruits to Andean spices.

In the afternoon, make your way to Barranco, Lima’s most bohemian and artistic neighborhood.

Once a beachside retreat for Lima’s elite, Barranco still boasts beautifully preserved mansions, some of which have been converted into stunning venues like Hotel B on San Martín Street, the famous Ayahuasca Bar, and the elegant Victoria Bar.

Take a stroll to admire street art along Cajamarca Street and the Bajada de Baños, a charming path that leads all the way down to the beach.

Don’t miss the iconic Puente de los Suspiros—a must-visit for a great photo—before exploring the lively shops, cafés, and restaurants that line the walkway.

If you have extra time, consider visiting:

Pedro de Osma Museum – Housed in a grand mansion with lush gardens, this museum showcases an impressive collection of Peruvian art from the 16th to 19th centuries.

As night falls, Barranco comes alive with an amazing selection of bars and restaurants—making it the perfect spot for drinks and a great night out in Lima.

Day 2 – The Historic Heart of Lima

Now it’s time to explore the Historic Center of Lima, a must-visit on your 21-day road trip through Peru and Bolivia.

Morning in the Historic Center

Start your day at the Plaza de Armas, the heart of old Lima. Here, you’ll find stunning colonial and traditional buildings, including the Cathedral of Lima, the Archbishop’s Palace, and the Government Palace—where you can even catch the Changing of the Guard if you time it right.

Next, head to the San Francisco Monastery, home to a breathtaking Baroque basilica and the eerie catacombs, where thousands of bones rest beneath the city streets.

From there, take a stroll down Jirón de la Unión, a lively pedestrian street lined with historic landmarks, shops, and cafés. Along the way, stop to admire the Church of La Merced, an architectural gem dating back to the 16th century.

At the end of the street, you’ll arrive at the grand Plaza San Martín, a spacious square surrounded by elegant, early 20th-century buildings.

Right here, you’ll find the legendary Gran Hotel Bolívar, a historic landmark that was once the epitome of luxury in the 1920s. Step inside to admire its vintage charm, and if you’re feeling bold, head to the bar and order a pisco sour—or better yet, the Cathedral Pisco Sour, a double-strength version of Peru’s iconic cocktail!

Afternoon at the Larco Museum

In the afternoon, hop in a cab and head to the Larco Museum in the Pueblo Libre district. This museum houses an impressive collection of pre-Columbian artifacts, spanning 4,000 years of history. It’s widely regarded as one of the best museums in Latin America!

After your visit, take a moment to relax on the museum’s terrace café, where you can sip on a cocktail, enjoy a coffee, or even have lunch while surrounded by a gorgeous, flower-filled garden.

Where to stay in Lima

For these two days, I recommend staying in Miraflores or Barranco, which are safe and well-located neighborhoods:

• Pariwana Hostel Lima: a very friendly youth hostel in the heart of Miraflores. Clean rooms, relaxed vibe, good Wi-Fi, with a restaurant, bar, and rooftop terrace. Dorm bed from only $13 USD and $50 USD for a private room!

• Casita Libertad Homestay: a small house located on a quiet and safe street in the Barranco neighborhood. Cozy atmosphere, very clean, with access to a fully equipped kitchen. Room from only $29 USD per night.

• Casa Andina: a 3-star hotel in Miraflores offering one of the best value-for-money stays in Lima. Modern hotel, recently renovated, with excellent service and an on-site restaurant. Buffet breakfast included, from $87 USD per night.

• Courtyard Lima Miraflores: a modern 4-star hotel perfectly located just steps from Kennedy Park. Comfortable and bright rooms, with a gym and a café-restaurant. From $165 USD per night.

2) Arequipa (1 day)

I suggest you go to Arequipa, the second most important city in the country, located in the Andes at 7,660 feet altitude.

Much quieter than the capital, it is known as the “White City” for its buildings built with sillar, a white volcanic stone.

Start with the Plaza de Armas and its majestic neo-Renaissance cathedral. Climb the bell tower and you will have a wonderful perspective of the square and its surroundings.

You will also find the Church of the Company of Jesus and the Church of Our Lady of Mercy.

You can continue with a visit to the famous Santa Catalina Convent, a must on a 3-week road trip through Peru and Bolivia. Built in the 16th century, in its heyday it housed more than 450 cloistered Carmelite nuns.

Allow several hours to wander through its red and ochre-colored streets and discover its fascinating history.

On Tuesdays and Wednesdays it is open until 8:00 p.m., which will allow you to visit it at night, see its beautiful lights and its mystical side. I walked it at night and totally recommend it!

Finally, do not miss the beautiful traditional neighborhood of Yanahuara with its narrow streets.

Visit the Yanahuara viewpoint to admire the Misti, Pichu Pichu and Chachani volcanoes.

It is an ideal place to taste the cuisine of Arequipa as there are several traditional “picanterias”.

I invite you to read:

• The Best Itinerary to Visit Arequipa in 1 Day

• Arequipa: 20 Things You Can’t Miss!

Go from Lima to Arequipa:

• By plane: 1h30 – Viva Air, Latam, Peruvian Airlines
• By bus: from 15h to 18h – Tepsa, Oltursa, Excluciva, Cruz del Sur, MovilTours

Where to stay in Arequipa

• Arequipay Hostel: Located a few blocks from the Main Square, this hostel offers very clean and bright dormitories. Perfect for budget travelers. Private rooms and shared dorms available. Basic breakfast served daily. From just $8 USD.

• Hotel Tierra Viva: Ideal for mid-range travelers. Just two blocks from the main square, it offers great value with comfortable rooms, Wi-Fi, and buffet breakfast included. From $60 USD per night.

• Hotel Los Tambos: A great choice for those seeking superior comfort. Located just 50 meters from the main square. Stylish rooms and a rooftop terrace with spectacular views of the city. À la carte breakfast with 5 menu options. From $71 USD per night.

• CIRQA – Relais & Châteaux: A stunning luxury hotel in the heart of Arequipa with a restaurant, bar, and rooftop terrace. Breakfast and dinner included with all rooms. From $475 USD per night.

3) Colca Canyon (2-3 days )

Located in the Arequipa region, the Colca Canyon is also another must-see during a 3-week tour of Peru and Bolivia.

Long considered the deepest canyon in the world, it was dethroned by its neighbor, the Cotahuasi Canyon.

However, with its 11,150 feet deep, it is still very impressive.

Besides marveling with the fabulous landscapes, you must go to the Cruz del Condor, an exceptional viewpoint to observe the condor of the Andes in full flight!

This is the program of a 2 days tour in the Colca Canyon:

• Departure from your hotel in Arequipa: you will pass through Pampa Cañahuas in the Aguada Blanca National Reserve where you will find lamas, alpacas and vicuñas.
• Photo stops at the Mirador de los Andes, Chucura crater and Mirador Chivay.
• Arrival to Chivay around 13h, you can have lunch and settle in the hotel
• Then you will have the option to go to the hot springs of La Calera or enjoy your free time
• In the evening, you will attend a dinner with a folkloric, music and dance show.
• The next day, visit the Cruz del Condor and the town of Yanque,
• Viewpoints Choquetipo y Artahuilque where you can see pre-Inca tombs and magnificent terraced crops.
• Return to Arequipa around 17h30

You can book here the tour which includes pick up at your hotel in Arequipa, entrance fees at the Colca, stops at the main attractions of the canyon:

• If you like trekking, you can also book the 2 Days Trek to the Colca or the 3 Days Trekk to the Colca Canyon with transportation from Arequipa, guide, meals and lodging!
• If you prefer to go on your own, I recommend you to read my Complete Article about the Colca Canyon so you can have all the practical information to set up your trip.

Going from Arequipa to the Colca Canyon

• By tourist van: the departure is from your hotel in Arequipa, early in the morning (3h). The arrival in Chivay is around 6h, then the stop at the Cruz del Condor around 8h, before arriving in Cabanaconde at 10h.
• By local bus: the trip takes 4h to Chivay, or 6h to Cabanaconde. Departure from the terminal of Arequipa with the company Andalucía.

Where to Stay in the Colca Canyon

• Paraiso Las Palmeras: the best option in Sangalle Oasis! The perfect place to relax during the Colca Canyon trek, with a pool surrounded by lush vegetation, an on-site restaurant, and good Wi-Fi. Breakfast included, from just $26 USD for a double room with private bathroom.

• La Granja del Colca: A true gem in Cabanaconde! Perched on a cliff, this hotel offers amazing views of the canyon—even from your room—and it’s one of the best spots to see condors in the morning. There are also friendly llamas in the garden. Fantastic value for money, from just $52 USD per night.

• Casa Andina Classic Colca: For a more comfortable stay in the Colca Valley, this charming rustic hotel in Chivay offers bungalows set in beautiful gardens. There’s also a great restaurant, breakfast buffet, spa, and even a telescope to admire the southern sky. From $72 USD per night.

• Colca Lodge Spa & Hot Springs: The perfect choice for a romantic stay in the Colca Valley. With direct access to natural hot springs, a spa, restaurant, and bar, this hotel features stylish rustic rooms with garden views. From $164 USD per night.

4) Cusco (1-2 days)

Now it is time to discover the famous capital of the Incas: Cusco!

At 11,150 feet of altitude, it is a city full of history that can be easily discovered by foot. It is certainly the best way to know the beauty of its architecture, a mixture of Inca alleys and colonial buildings.

The ideal would be to visit Cusco in 2 or 3 Days, although it would be possible to do it in 1 day.

1st day -In the morning we start the sightseeing by the Plaza de Armas, the center of the city.

The cathedral and the Iglesia de la Compañía are emblematic places to be admired, as well as the colonial buildings.

Visit San Blas, the artists’ quarter of Cusco. You will find streets with lots of charm, restaurants, art galleries, boutiques, etc.

I recommend you to follow this route:

• From the square, head to Plazoleta de las Nazarenas where the interesting MAP (Museo de Arte Colombiano) is located.
• Go down Calle Palacio to reach the well-known Hatunrumiyok street and its 12-angled Inca stone, a magnificent example of Inca engineering.
• Continue to the end of the street and go up the Cuesta de San Blas (take your time, it is hard!), you will arrive at the beautiful Plazoleta de San Blas.

Stroll around San Blas, the streets have a lot of charm. There are also a lot of nice restaurants, it is an ideal place to eat or have a drink.

2nd day- In the morning, start with a visit to the Coricancha.

The Temple of the Sun, dedicated to the god “Inti”, was the most sacred place of the Inca Empire and was decorated with fine gold leaf.

It´s here where the sovereigns paid homage to them and where their mummies were preserved. It was destroyed by the conquistadors who built on top of this place, the convent of Santo Domingo in 1534.

Then go to the San Pedro Market. You will see a great variety of potatoes, quinoa and other Andean cereals, fruits, vegetables and cheeses.

In the afternoon, visit the 4 archaeological sites very close to Cuzco:

• Sacsayhuaman: more less 1 mile from Cuzco, you´ll find a great fortress in the shape of a puma, a sacred animal for the Incas. Its construction lasted 50 years and it would have taken 20,000 men, no more and no less! As it overlooks the city, the panoramic view is spectacular.
• Qenko: its meaning in quechua is labyrinth, because of a whole network of subway galleries. You can also see a semicircular amphitheater that must have been an important place of ceremonies.
• Tambomachay: it was a place destined to the cult of water and the rest of the Inca gods. Nowadays, its fountains and waterfalls are still running.
• Puca Pucara: Tambomachay’s neighbor, the “red fortress” named for the color of its stones when the sun sets. This place was built to ensure the defense of Cusco.

If you have little time and want to make the most of Cusco, I recommend this guided tour of the historic center of Cusco.

It also includes the 4 Inca archaeological sites and pick up from your hotel. Book it here:

You can also read:

• Cusco: What to Do in 1 Day
• 2 or 3 Days in Cusco: What to Do and See?
• Cusco: The 30 Best Things to See and Visit
• Cusco: 19 Free Activities + Saving Tips

Going from Arequipa to Cusco:

• By plane: 1h- Companies: Latam, Peruvian Airlines, Avianca (they are the only ones that offer this route with direct flight).
• By bus: approximately 10h – Companies: Cruz del Sur, Civa, Oltursa, MovilTours (you can make the trip during the night because the route is quite comfortable and this allows you to save time).
• To go from the Colca Canyon to Cusco: the bus company 4M makes the route Chivay-Cusco on Mondays, Wednesdays and Fridays (departure 7h – arrival 17h30).

Where to Stay in Cusco

• Backpacker La Bo’M: One of the best hostels in Cusco. Founded by Sarah, a French expat, it includes a delicious crêperie next door. Perfectly located in the charming neighborhood of San Blas, it offers good Wi-Fi, a cozy vibe, and of course, amazing crêpes to start your day! Dorms from only $13 USD and private rooms from $33 USD.

• La Casona Real Cusco: For those looking for more comfort, this charming traditional-style guesthouse is located on a quiet street just steps from the Plaza de Armas. Impeccably clean, with hot water, great Wi-Fi, and a warm welcome. Breakfast included, all from just $76 USD per night!

• Hotel Tierra Viva Cusco San Blas: In the lovely San Blas neighborhood, this upscale hotel offers spacious rooms with very comfortable beds. Its modern décor with local touches and peaceful interior courtyard make for a relaxing stay. Buffet breakfast included. From $98 USD per night!

• Antigua Casona San Blas: A chic and intimate 4-star hotel in San Blas. It features very comfortable rooms, a warm atmosphere, and a tasteful blend of modern and traditional décor. Don’t miss their Piedra & Sal restaurant, one of Cusco’s best. Excellent breakfast included. From $250 USD per night.

• Palacio del Inka, a Luxury Collection Hotel: For a romantic stay in Cusco, this 5-star gem is housed in a spectacular colonial building across from Coricancha, with roots dating back to Inca times. Enjoy the indoor pool, gym, spa, bar, and restaurant. Delicious breakfast included. From $325 USD per night.

5) The Sacred Valley (2-3 days)

The Sacred Valley is a fundamental visit of a 20-21 day itinerary in Peru and Bolivia as there is a lot to do.

With a good organization, you will be able to visit the most important sites in 2 days.

1st Day – Start with Pisac and Ollantaytambo, the two most important Inca archaeological sites in the Sacred Valley.

• Pisac is a town known for its market that takes place on Sundays, Tuesdays and Thursdays. Its archaeological center is one of the most important in the country. The place had three functions: military, religious and agricultural.
• Strategically located, Ollantaytambo was one of the most important towns of the Inca empire. Today it is a charming little town that has preserved its original layout.

Then, visit the village of Chinchero, with small cobblestone streets and white houses. It is known for its textile art. It is the ideal place to discover the process of its manufacture, the spinning, how it is woven, the nautral dyes.

You will find in the market tapestries and handmade clothes, the prices are better than in other places.

If you want to see the most of the Sacred Valley in a short time, without wasting time in transportation, I suggest you to take a tour from Cusco.

I recommend this tour of Pisac, Ollantaytambo and Chinchero, with lunch included:

Day 2 – Today discover Maras and Moray.

Take the road to the site of the Salineras de Maras, one of the most impressive areas in the region!

Here, a spring of salt-rich water pours into more than 3,000 ponds, which offer a stunning view, all in white, like something out of a fairy tale.

Some 800 families run these ponds as a cooperative and produce an average of 180 tons of salt per year.

Not far from there is Moray, an ancient Inca agricultural research center.

Here we find different circular terraces built to create about twenty microclimates.

The temperature variation between the center and the extremities has allowed to carry out different experiments and to cultivate numerous exotic species.

I recommend this tour of the salt mines of Maras and the terraces of Moray:

Day 3– If you prefer to give yourself more time in the valley and spend 3 days instead of 2 days, I recommend that you concentrate on Ollantaytambo since besides being extremely pleasant to walk around the area it has lots of free and interesting attractions.

You could also spend the night here before going to Machu Picchu as there is a train station.

The best, of course, is its fortress, which also offers a magnificent panoramic view of the surrounding area.

Where to Stay in Ollantaytambo

• Las Portadas: This is the best budget option in Ollantaytambo. A typical local house with a lovely garden and mountain views, just 5 minutes from the main square and 15 minutes from the train station. Rooms from just $23 USD with breakfast included.

• Casa de la Chola: A beautiful room in a charming lodge located just outside of town, about 10 minutes from Ollantaytambo train station. Perfect for nature lovers. From $60 USD per night, with a breakfast that’s a true treat for food lovers.

• Apu Lodge: A lovely hotel with a garden and fantastic views of the mountains and Inca ruins. Very peaceful location, with spacious and comfortable rooms that can host up to 5 people. Friendly staff. Excellent breakfast included. From $93 USD per night!

• El Albergue Ollantaytambo: A countryside-style hotel located right at the Ollantaytambo train station, perfect for catching the early train to Machu Picchu. Comfortable rooms, a beautiful green garden, an organic farm, and a peaceful setting. Onsite you’ll also find an excellent restaurant, a coffee roastery, and a craft distillery. Breakfast included. From $275 USD per night!

6) Machu Picchu (1-2 days)

This is the most awaited moment of a 3-week tour of Peru and Bolivia: Machu Picchu, one of the 7 new wonders of the world!

Abandoned after the fall of the mighty Inca empire in the 16th century, the site was unveiled by Hiram Bingham in 1911.

It seems that Machu Picchu had a dual vocation: residential (for the elite) and religious. It was really a small city, with houses, its temple, its squares, its agricultural area.

Machu Picchu is located between two mountains, at 8,000 feet of altitude: the Huayna Picchu (the young mountain) and the Machu Picchu (the old mountain).

If you wish to take a guided tour of Machu Picchu, you will easily find guides offering their services in different languages at the entrance of the site.

It is very important to book your tickets to Machu Picchu in advance:

• Ticket to Machu Picchu
• Ticket for Machu Picchu + Wayna Picchu (book it several months in advance)
• Ticket for Machu Picchu + Machu Picchu Picchu Mountain

To choose which type of ticket suits you, I invite you to read: Huayna Picchu and Machu Picchu Mountain: Which Are the Differences?

Getting to Machu Picchu:

Option 1: train – 3h from Cusco or 1h30 from Ollantaytambo.

It is the fastest way to get there and the scenery is really amazing but I recommend that you book your train tickets to Aguas Calientes in advance, to make sure you can get on the train at the time that suits you.

You can buy your train tickets to Aguas Calientes from Cusco or Ollantaytambo here:

Option 2: trek to Machu Picchu – although remember that the only one that goes directly to Machu Picchu is the Inca Trail, while the others go through Aguas Calientes.

You can book your trek here:

• Inca Trail Trek (4 days) – to be booked several months in advance!
• Inca Trail Trek short version (2 days)
• Salkantay Trek (5 days)
• Inca Jungle Trek (4 days) – perfect if you like the adrenaline rush
• Lares Trek (4 days)

Option 3 – by bus and walking – the most economical and the longest way

You have to take a colectivo from Cusco to Hidroeléctrica (7h) and walk to Aguas Calientes (2h30-3h)

And remember that when you arrive in Aguas Calientes, you will have to take the bus up to Machu Picchu (20 min).You can book your bus tickets here:

Where to Stay in Aguas Calientes (Machu Picchu Pueblo)

• Municipal Camping: The cheapest option is camping in Aguas Calientes, just 20 minutes from downtown. For only 15 soles per tent, you get access to restrooms, cold showers, and a cooking area. Don’t forget to bring toilet paper and food beforehand. Not recommended from December to February due to heavy rains.

• Nativus Hostel Machu Picchu: A clean and colorful hostel with a rooftop terrace, happy hour bar, and restaurant. Great location away from the noise. Breakfast included. Dorm beds from just $14 USD and private rooms from $54 USD.

• Panorama B&B: Just a few steps from the market, train station, and Machu Picchu bus stop. Offers panoramic views of the river and surrounding mountains. A comfortable hotel with a warm welcome from Christophe, the owner, always ready to share local tips. From $101 USD per night.

• Casa del Sol Boutique Hotel 4*: Ideal for a romantic stay, with rooms offering river views and jacuzzi, spa, and pool access. Breakfast and dinner included at the Manko Restaurant. From $227 USD per night.

• Inkaterra Machu Picchu Pueblo Hotel 5*: This stunning eco-lodge on the banks of the Vilcanota River is the best option for a luxury stay in Peru. Set in a private 5-hectare garden home to 372 orchid species, 162 bird species, 108 butterfly species, and even a freshwater waterfall. Breakfast and dinner included. From $448 USD per night.

7) Lake Titicaca and Copacabana (2-3 days)

Now let’s visit the highest navigable lake in the world: Lake Titicaca, at 12,470 feet above sea level

As you are lucky enough to visit Peru and Bolivia for 21 days, I advise you to give priority to the Bolivian side as the city of Copacabana is much nicer than Puno.

It is recommended to visit it from Bolivia and not from Peru since the Bolivian city of Copacabana is a place with a lot of charm unlike Puno in Peru. Besides the Isla del Sol is a true jewel.

Day 1 – First discover Copacabana, which means in Quechua “view over the lake”.

It is a small, beautiful and quiet city, that thrives outta tourism. You will be pleased to rest here after the Machu Picchu stage.

Visit its great Cathedral, all white and beautiful and if you can, try the trout that comes directly from the lake.

In the afternoon, I strongly advise you to go see the sunset from the viewpoint located on Mount Calvario: you will have a view over the immensity of the lake, and the sunset offers amazing colors over the city and magical reflections on the water.

Go from Cusco to Puno, and then Copacabana:

• By plane: Cusco – Juliaca (With stopover in Lima) with Latam or Sky. Then take a bus from Juliaca to Puno and from Puno to Copacabana.
• By train: Cusco-Puno (10h30) with PeruRail and then take the bus from Puno to Copacabana (3h).
• By bus (in 2 stages): Cusco-Puno: 6h30 (Buy your tickets for the direct bus now!) and another bus Puno- Copacabana: 3h- Companies: Trans Titicaca, Transzela.
• By tourist bus: another option is to do the Cusco-Puno route by tourist bus which includes visits to interesting places on the way (the church of Andahuaylillas, Raqchi, the museum of Pucara) and a buffet lunch. You can book your tickets here:

2nd day- The next day, early in the morning, head to the port to buy the ticket, for the lake crossing to Isla del Sol.

You can reach the island either north to the town of Challapampa or south to the town of Yumani.

I advise you to arrive in Challapampa and then walk south and depart from Yumani.

If you would like to leave in the afternoon, boats leave later on the south side to return to Copacabana.

Here are the boat schedules (to be confirmed on the spot):

– Departure from Copacabana: 8h30 or 13h30 to Challapampa or Yumani

– Return from Challapampa: 8:30 am, 10:30 am and 1:30 pm

– Return from Yumani: 8:30 am, 10:30 am and 4:30 pm

As soon as you arrive, you can choose to cross the island in two ways: either the crete trail or the beach trail.

Since I only stayed for one day, I couldn’t do the outward journey on one trail and the return on the other.

The path of the hills allowed me to have a panoramic view of the island. You cannot believe that it is a lake, because it is immense!

It´s true that at certain times of the year there may be more travelers on the trails, but when I went in April, I felt alone in the world.

To discover on the island: Chinkana, Challa and also the Pilkokaina Palace.

Where to Stay in Copacabana

• Hostal Piedra Andina: With its pretty white facade, multiple terraces and balconies, it almost feels like Greece. Overlooking the lake, it offers comfortable rooms, breakfast included, and access to a shared kitchen. From only $30 USD per night!

• Hostal Las Olas: A very original hotel that looks like a colorful fairytale village. It boasts stunning views of Copacabana Bay, hammocks for relaxing, llamas and alpacas in the garden, and access to a kitchen. If you’re traveling on a mid-range budget, this place is a must! From $75 USD.

• Hotel Rosario Lago Titicaca: Looking for a high-end stay on Lake Titicaca? This European-style hotel is located right by the water and offers stunning sunset views through its large windows and from its terrace. From $85 USD per night.

8) La Paz (2 days)

The next stop of this 3-week stay in Peru and Bolivia: La Paz (12,000 feet altitude), the capital of Bolivia and the highest capital in the world.

With a 3,280 feet difference in altitude between the wealthy neighborhoods and the poor neighborhoods, you will have to make a lot of effort with your legs as its streets are very steep.

Fortunately it has a well-developed urban cable car (the longest and highest in the world!).

Day 1 – Visit the city of La Paz

Discover the Mercado Rodriguez, also the famous Mercado de las brujas where there are all kinds of magic potions, then to the Plaza Murillo and the cathedral of San Francisco.

Then you could go to the Mirador Kili Kili to have a panoramic view of the city.

If you are “foodie”, I suggest you take this Gastronomic Tour of La Paz in the afternoon with a guide who will make you discover the local specialties.

2nd Day- If you like adventure and adrenaline, I propose you to make the descent of the famous Ruta de la Muerte by mountain bike.

It´s such an unforgettable experience!

Choose your agency well, as it is essential that you get good equipment and bikes in good condition.

You can book the Death Road tour with a well-established agency here:

If you had time left, you could go see a Cholitas Wrestling show. It’s a cholitas wrestling match, those Bolivian wrestlers who are characterized by wearing traditional dress.

Go from Copacabana to La Paz:

• By bus: 4h- Companies: Trans Titicaca, Vicuña Travel. Departure at 13h30 or 18h30 from Sucre Square.

Where to Stay in La Paz

• Lhamourai Living Apartments: If you’re looking for a quiet and affordable stay in La Paz, this is a great value-for-money option. These are fully-equipped apartments and studios for 2 to 6 people, with living room and kitchen. Well located and close to the cable car. From only $40 USD!

• Hotel Rosario La Paz: A great choice for a superior stay in La Paz, centrally located. This charming colonial-style boutique hotel has a lovely terrace, heated rooms, and a full buffet breakfast. From $90 USD per night.

• La Casona Hotel Boutique: For a luxury stay in La Paz, this is without a doubt the top-rated hotel in its category. Housed in a restored colonial mansion and declared a Heritage Site of La Paz, it combines historic charm with modern comfort. From $190 USD per night.

9) Salar de Uyuni and Sud Lipez (3 days)

One of my favorite moments of this 3-week trip through Peru and Bolivia was to discover the Salar de Uyuni and Sud Lipez.

The departure can be made from the cities of Uyuni or Tupiza, the latter is located further south. I recommend you to leave from Uyuni.

The classic circuit to visit the Salar de Uyuni is 3 days with full board (transport, meals, lodging).

Don’t forget to bring warm clothes, thick wool socks and a sleeping bag to protect you from the extreme temperatures, even if you are lodged, the accommodations are quite basic, there is no heating and you will climb to 16,400 feet of altitude!

1st Day – Departure to the Salar de Uyuni at around 10:30 am.

You will first head to the train cemetery to take some photos of locomotive and wagon skeletons, then visit the Colchani salt museum, before arriving at the famous salt desert.

During the rainy season, the desert is covered with a thin layer of water, and gives the impression of walking on a huge mirror. Take the opportunity to take original photos playing with perspective.

You will be taken to the Incahuasi island or cactus island. In the middle of the desert, it is a mini hill covered with cactus.

At night you will sleep in a salt hotel, basic but good!

2nd Day- You will discover, some lagoons, the Árbol de Piedra (stone tree) in the middle of a lunar landscape of the Dali desert.

You will arrive at the Laguna Colorada, with an ecosystem of great biological diversity, it is the ideal habitat for nesting Andean flamingos.

Day 3– On the last day, you will head to the hot springs, discover geysers, and finally the Laguna Verde at the foot of the Licancabur volcano – where sacrifices were made.

These will be intense days, both for the physical effort (cold, high altitude, getting up early) and for the beauty and diversity of the landscape.

You will return to Uyani, and from there to La Paz to take your flight back.

You will travel from La Paz to Uyuni:

• By plane: 1h – With BOA
• By bus: 9h to 10h – Companies; Trans Omar, Panasur, Cruz del Norte, Emperador, Trans Titicaca. Be careful, other companies also propose the route but it is not always direct and makes a stopover in Oruro.

Where to Stay in Uyuni

• Piedra Blanca Backpacker Hostel: A great budget-friendly option in Uyuni, simple but with clean and comfortable rooms, access to a kitchen, good Wi-Fi, and hot water. From just $12 USD for dorms or $32 USD for a private room!

• Hotel Jardines de Uyuni: If you’re looking for extra comfort, this is a cozy hotel with a fireplace in the central courtyard, a heated pool, sauna, and a delicious restaurant. From $185 USD.

• Hotel de Sal Luna Salada: For a truly romantic hotel in Uyuni, this is a fabulous choice. Located right on the edge of the salt flats, it offers stunning sunset views, spacious rooms with large windows, fireplaces in common areas, a spa with treatments, and a jacuzzi. From $260 USD.

What is the best time to travel 3 weeks in Peru and Bolivia?

If you want to make the most of your 3-week itinerary in Peru and Bolivia, choosing the right season is essential. This route crosses diverse regions—deserts, high mountains, and jungle—so climate plays a big role.

Dry season (May to October) – The best time to go

I highly recommend planning your trip between May and October. It’s the best time for clear skies, dry trails, and stunning views at Machu Picchu, Lake Titicaca, and the Salar de Uyuni.

• Stable weather and dry roads — ideal for hikes, bus rides, and scenic train journeys.
• Clear views of top sights like the Sacred Valley, South Lípez, and Andean peaks.
• Fully dry Uyuni Salt Flats — perfect for walking and taking perspective photos.

Keep in mind:

• Cold nights at high altitudes (especially in La Paz, Puno, and Uyuni) — pack warm layers!
• High tourist season in popular areas like Cusco and Machu Picchu — book in advance.

Rainy season (November to April) – Not ideal for this itinerary

Traveling from January to March means frequent rain, especially in the Andes. It’s not impossible, but some places may become inaccessible or affected by bad weather.

Pros: The Uyuni Salt Flats turn into a giant mirror — breathtaking for photographers.

Cons:

• Slippery trails on treks like the Inca Trail, with risk of temporary closures.
• Disrupted travel between La Paz and Uyuni due to weather or road conditions.
• Unpredictable access to the lagoons and desert of South Lípez.

So, when should you go?

The best time for this Peru and Bolivia 3-week itinerary is definitely May to October, when you can travel worry-free and enjoy every destination in its best condition.

As an alternative, the shoulder months—late April or early November—can offer fewer crowds and greener landscapes in the Sacred Valley, with relatively low rain risk.

How to handle altitude acclimatization during a trip to Peru and Bolivia?

Altitude can be a challenge in places like Cusco, Puno, La Paz, or Uyuni. Everyone reacts differently, but it’s best to prepare and take it easy. I always take some basic precautions when traveling at altitude.

Here are my go-to tips to avoid altitude sickness on this itinerary:

• Drink plenty of water — dehydration happens faster at high elevation.
• Avoid alcohol and heavy meals at first — your body needs time to adapt.
• Take it slow during the first few days — skip intense hikes at the start.
• Drink coca tea — a traditional and effective remedy, available for free in most hotels and easy to find in cafés.

This itinerary is designed with a gradual ascent to help your body adapt. You should be fine, but always listen to your body and take breaks when needed.

Book Your Flight at the Best Price

Planning a trip to Peru? To get the best deal on your flights, I recommend using this flight comparison tool, in partnership with Skyscanner.

It’s the easiest way to find the lowest prices for both international flights and domestic flights within Peru—ensuring you pay the best rate with no hassle!

Car Rental in Peru: My Top Recommendation

Thinking about renting a car in Peru? Great idea!

It’s one of the best ways to explore Peru freely and access destinations that are off the beaten path—especially if you’re planning to visit remote areas like the Sacred Valley, Huaraz, or the coast near Paracas.

Personally, I always use Booking.com Cars to rent a car in Peru, and here’s why I keep coming back:

• Easy price comparison between all major rental companies—so you’re sure to get the best deal.
• Free cancellation on most options, which is perfect if your itinerary changes.
• Affordable insurance options with better coverage than most rental agencies—so you save money and avoid surprises.

Click the button below to check current car rental deals in Peru and book with confidence:

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